MIST Antibody
| Code | Size | Price |
|---|
| PSI-57-368-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer, CLNK, MIST
Application Note:
For WB starting dilution is: 1:1000
Background:
MIST is a member of the SLP76 family of adaptors (see
LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the
regulation of immunoreceptor signaling, including PLC-gamma (PLCG1;
MIM 172420)-mediated B cell antigen receptor (BCR) signaling and
FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell
degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al.,
2000, 2001 [PubMed 10744659] [PubMed 11463797]).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Cronin, S., et al. Eur. J. Hum. Genet. 17(2):213-218(2009)
- Goitsuka, R., et al. J. Biol. Chem. 276(38):36043-36050(2001)
- Goitsuka, R., et al. Int. Immunol. 12(4):573-580(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
NCBI Gene ID #:
116449
NCBI Official Name:
Cytokine-dependent hematopoietic cell linker
NCBI Official Symbol:
CLNK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q7Z7G1
Protein GI Number:
166217263
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q7Z7G1
User NOte:
Optimal dilutions for each application to be determined by the researcher.