TRAF3IP1 Antibody

ProSci
Product Code: PSI-59-480
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-480-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Further Information

Additional Names:
TRAF3-interacting protein 1, Interleukin-13 receptor alpha 1-binding protein 1, Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3, TRAF3IP1, IFT54, MIPT3
Application Note:
For WB starting dilution is: 1:1000
Background:
TRAF3IP1 play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Guo, C.W., et al. Proteomics 10(12):2337-2347(2010)
  • Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
  • Tomppo, L., et al. Biol. Psychiatry 65(12):1055-1062(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRAF3IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human TRAF3IP1.
NCBI Gene ID #:
26146
NCBI Official Name:
TRAF3-interacting protein 1
NCBI Official Symbol:
TRAF3IP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q8TDR0
Protein GI Number:
74727348
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8TDR0
User NOte:
Optimal dilutions for each application to be determined by the researcher.