ITGAE Antibody
| Code | Size | Price |
|---|
| PSI-55-218-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE
Application Note:
For WB starting dilution is: 1:1000
Background:
Integrins are heterodimeric integral membrane proteins
composed of an alpha chain and a beta chain. ITGAE encodes an
I-domain-containing alpha integrin that undergoes
post-translational cleavage in the extracellular domain, yielding
disulfide-linked heavy and light chains. In combination with the
beta 7 integrin, this protein forms the E-cadherin binding integrin
known as the human mucosal lymphocyte-1 antigen. This protein is
preferentially expressed in human intestinal intraepithelial
lymphocytes (IEL), and in addition to a role in adhesion, it may
serve as an accessory molecule for IEL activation. [provided by
RefSeq].
Background References:
- Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
- Liu, Y.H., et al. Ophthalmology 117(8):1645-1651(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITGAE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1146-1173 amino acids from the C-terminal region of human ITGAE.
NCBI Gene ID #:
3682
NCBI Official Name:
Integrin alpha-E
NCBI Official Symbol:
ITGAE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
130 kDa
Protein Accession #:
P38570
Protein GI Number:
226694184
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P38570
User NOte:
Optimal dilutions for each application to be determined by the researcher.