IFNGR1 Antibody

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ProSci
Product Code: PSI-56-568
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-568-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).
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Western blot analysis in Y79 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, CD119, IFNGR1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq].
Background References:
  • Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IFNGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-489 amino acids from the C-terminal region of human IFNGR1.
NCBI Gene ID #:
3459
NCBI Official Name:
Interferon gamma receptor 1
NCBI Official Symbol:
IFNGR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
P15260
Protein GI Number:
124474
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P15260
User NOte:
Optimal dilutions for each application to be determined by the researcher.