TNFSF14 Antibody
| Code | Size | Price |
|---|
| PSI-57-843-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, CD258, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form, TNFSF14, HVEML, LIGHT
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) ligand family. This protein is a ligand for
TNFRSF14, which is a member of the tumor necrosis factor receptor
superfamily, and which is also known as a herpesvirus entry
mediator (HVEM). This protein may function as a costimulatory
factor for the activation of lymphoid cells and as a deterrent to
infection by herpesvirus. This protein has been shown to stimulate
the proliferation of T cells, and trigger apoptosis of various
tumor cells. This protein is also reported to prevent tumor
necrosis factor alpha mediated apoptosis in primary hepatocyte. Two
alternatively spliced transcript variant encoding distinct isoforms
have been reported.
Background References:
- Stiles, K.M., et al. J. Virol. 84(22):11646-11660(2010)
- Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TNFSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the Central region of human TNFSF14.
NCBI Gene ID #:
8740
NCBI Official Name:
Tumor necrosis factor ligand superfamily member 14
NCBI Official Symbol:
TNFSF14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
O43557
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
O43557
User NOte:
Optimal dilutions for each application to be determined by the researcher.