Mouse Hck Antibody
| Code | Size | Price |
|---|
| PSI-58-266-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein kinase HCK, B-cell/myeloid kinase, BMK, Hematopoietic cell kinase, Hemopoietic cell kinase, p56-HCK/p59-HCK, Hck
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the Src
family of tyrosine kinases. This protein is primarily hemopoietic,
particularly in cells of the myeloid and B-lymphoid lineages. It
may play a role in the innate immune response and the STAT5
signaling pathway. Alternative translation initiation site usage,
including a non-AUG (CUG) codon, results in the production of two
different isoforms, that have different subcellular localization.
Background References:
- Verollet, C., et al. J. Immunol. 184(12):7030-7039(2010)
- Ruschmann, J., et al. Exp. Hematol. 38(5):392-402(2010)
- Lowell, C.A., et al. J. Cell Biol. 133(4):895-910(1996)
- Lowell, C.A., et al. Blood 87(5):1780-1792(1996)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Hck antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of mouse Hck.
NCBI Gene ID #:
15162
NCBI Official Name:
Tyrosine-protein kinase HCK
NCBI Official Symbol:
Hck
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
P08103
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P08103
User NOte:
Optimal dilutions for each application to be determined by the researcher.