M6PR Antibody
| Code | Size | Price |
|---|
| PSI-61-509-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, M6PR, MPR46, MPRD
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a receptor for
mannose-6-phosphate groups on lysosomal enzymes. The receptor forms
a homodimer or homotetramer for intracellular targeting of
lysosomal enzymes and export of newly synthesized lysosomal enzymes
into the cell secretions. The receptor is an integral membrane
protein which localizes to the trans-Golgi reticulum, endosomes,
and the plasma membrane.
Background References:
- Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
- Op den Brouw, M.L., et al. Virology 393(1):84-90(2009)
- Schimanski, L.M., et al. Blood Cells Mol. Dis. 43(2):180-193(2009)
- Rodriguez-Gabin, A.G., et al. Exp. Cell Res. 315(13):2215-2230(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human M6PR.
NCBI Gene ID #:
4074
NCBI Official Name:
Cation-dependent mannose-6-phosphate receptor
NCBI Official Symbol:
M6PR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
P20645
Protein GI Number:
127293
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Immunology,Signal Transduction
Swissprot #:
P20645
User NOte:
Optimal dilutions for each application to be determined by the researcher.