CSF1R Antibody

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ProSci
Product Code: PSI-63-033
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-033-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from U-937 cell line, using CSF1R Antibody at 1:1000.
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Confocal immunofluorescent analysis of CSF1R Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
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Western blot analysis of lysate from U-937 cell line, using CSF1R Antibody at 1:1000.
Confocal immunofluorescent analysis of CSF1R Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Documents

Further Information

Additional Names:
Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1R, FMS
Application Note:
For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
Background References:
  • Guey,L.T., et.al., Eur. Urol. 57 (2), 283-292 (2010)
  • Wooten,E.C., et.al., PLoS ONE(1), E8830 (2010)
  • Hosgood,H.D. III, et.al., Respir Med 103 (12), 1866-1870 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CSF1R antibody is generated from rabbits immunized with CSF1R recombinant protein.
NCBI Gene ID #:
1436
NCBI Official Name:
Macrophage colony-stimulating factor 1 receptor
NCBI Official Symbol:
CSF1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
P07333
Protein GI Number:
547770
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P07333
User NOte:
Optimal dilutions for each application to be determined by the researcher.