PPP3CA Antibody

ProSci
Product Code: PSI-57-249
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-249-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A375 cell line lysates (35ug/lane).

Western blot analysis in A375 cell line lysates (35ug/lane).

Further Information

Additional Names:
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA
Application Note:
For WB starting dilution is: 1:1000
Background:
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
Background References:
  • He, Z.H., et al. Eur. J. Appl. Physiol. 110(4):761-767(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Chiocco, M.J., et al. Subst Use Misuse 45(11):1809-1826(2010)
  • Yang, D., et al. Int. J. Mol. Med. 26(1):159-164(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This PPP3CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human PPP3CA.
NCBI Gene ID #:
5530
NCBI Official Name:
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
NCBI Official Symbol:
PPP3CA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q08209
Protein GI Number:
1352673
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction,
Swissprot #:
Q08209
User NOte:
Optimal dilutions for each application to be determined by the researcher.