PTAFR Antibody
Code | Size | Price |
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PSI-61-919-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR
Application Note:
For WB starting dilution is: 1:1000
Background:
PTAFR shows structural characteristics of the rhodopsin
(MIM 180380) gene family and binds platelet-activating factor
(PAF). PAF is a phospholipid
(1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been
implicated as a mediator in diverse pathologic processes, such as
allergy, asthma, septic shock, arterial thrombosis, and
inflammatory processes.
Background References:
- Davila, S., et al. Genes Immun. (2010) In press :
- Hirota, N., et al. J. Biol. Chem. 285(8):5931-5940(2010)
- Kaneko, K., et al. J. Invest. Dermatol. 129(11):2567-2573(2009)
- Melnikova, V.O., et al. J. Biol. Chem. 284(42):28845-28855(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.
NCBI Gene ID #:
5724
NCBI Official Name:
Platelet-activating factor receptor
NCBI Official Symbol:
PTAFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P25105
Protein GI Number:
129557
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction,Growth Factor
Swissprot #:
P25105
User NOte:
Optimal dilutions for each application to be determined by the researcher.