CCRL2 Antibody
| Code | Size | Price |
|---|
| PSI-58-542-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
C-C chemokine receptor-like 2, Chemokine receptor CCR11, Chemokine receptor X, Putative MCP-1 chemokine receptor, CCRL2, CCR11, CCR6, CKRX, CRAM, HCR
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a chemokine receptor like protein, which
is predicted to be a seven transmembrane protein and most closely
related to CCR1. Chemokines and their receptors mediated signal
transduction are critical for the recruitment of effector immune
cells to the site of inflammation. This gene is expressed at high
levels in primary neutrophils and primary monocytes, and is further
upregulated on neutrophil activation and during monocyte to
macrophage differentiation. The function of this gene is unknown.
This gene is mapped to the region where the chemokine receptor gene
cluster is located.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
- Leick, M., et al. Immunology 129(4):536-546(2010)
- Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human CCRL2.
NCBI Gene ID #:
9034
NCBI Official Name:
C-C chemokine receptor-like 2
NCBI Official Symbol:
CCRL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
O00421
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction,Growth Factor
Swissprot #:
O00421
User NOte:
Optimal dilutions for each application to be determined by the researcher.