XCR1 Antibody
| Code | Size | Price |
|---|
| PSI-56-196-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1, XCR1, CCXCR1, GPR5
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a chemokine receptor
belonging to the G protein-coupled receptor superfamily. The family
members are characterized by the presence of 7 transmembrane
domains and numerous conserved amino acids. This receptor is most
closely related to RBS11 and the MIP1-alpha/RANTES receptor. It
transduces a signal by increasing the intracellular calcium ions
level. The viral macrophage inflammatory protein-II is an
antagonist of this receptor and blocks signaling. Two alternatively
spliced transcript variants encoding the same protein have been
found for this gene.
Background References:
- Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)
- Crozat, K., et al. J. Exp. Med. 207(6):1283-1292(2010)
- Bachem, A., et al. J. Exp. Med. 207(6):1273-1281(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This XCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-333 amino acids from the C-terminal region of human XCR1.
NCBI Gene ID #:
2829
NCBI Official Name:
Chemokine XC receptor 1
NCBI Official Symbol:
XCR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P46094
Protein GI Number:
1170008
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction,Growth Factor
Swissprot #:
P46094
User NOte:
Optimal dilutions for each application to be determined by the researcher.