HRH1 Antibody
Code | Size | Price |
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PSI-57-725-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Histamine H1 receptor, H1R, HH1R, HRH1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Histamine is a ubiquitous messenger molecule released from
mast cells, enterochromaffin-like cells, and neurons. Its various
actions are mediated by histamine receptors H1, H2, H3 and H4. This
gene was thought to be intronless until recently. The protein
encoded by this gene is an integral membrane protein and belongs to
the G protein-coupled receptor superfamily. It mediates the
contraction of smooth muscles, the increase in capillary
permeability due to contraction of terminal venules, the release of
catecholamine from adrenal medulla, and neurotransmission in the
central nervous system. Multiple alternatively spliced variants,
encoding the same protein, have been identified. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Notcovich, C., et al. Exp. Cell Res. 316(3):401-411(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HRH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human HRH1.
NCBI Gene ID #:
3269
NCBI Official Name:
Histamine H1 receptor
NCBI Official Symbol:
HRH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P35367
Protein GI Number:
547645
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction,Growth Factor
Swissprot #:
P35367
User NOte:
Optimal dilutions for each application to be determined by the researcher.