PANX2 Antibody

ProSci
Product Code: PSI-60-373
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-373-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Pannexin-2, PANX2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Ambrosi, C., et al. J. Biol. Chem. 285(32):24420-24431(2010)
  • Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
  • Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
  • Lai, C.P., et al. Oncogene 28(49):4402-4408(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PANX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the C-terminal region of human PANX2.
NCBI Gene ID #:
56666
NCBI Official Name:
Pannexin-2
NCBI Official Symbol:
PANX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q96RD6
Protein GI Number:
296439257
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q96RD6
User NOte:
Optimal dilutions for each application to be determined by the researcher.