PMP22 Antibody
Code | Size | Price |
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PSI-58-253-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010) Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22.
NCBI Gene ID #:
5376
NCBI Official Name:
Peripheral myelin protein 22
NCBI Official Symbol:
PMP22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
Q01453
Protein GI Number:
266803
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q01453
User NOte:
Optimal dilutions for each application to be determined by the researcher.