MOG Antibody

ProSci
Product Code: PSI-59-661
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-661-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Myelin-oligodendrocyte glycoprotein, MOG
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Boyle, L.H., et al. J. Neurochem. 102(6):1853-1862(2007)
  • Allamargot, C., et al. J. Neurochem. 101(2):298-312(2007)
  • Delarasse, C., et al. J. Neurochem. 98(6):1707-1717(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This MOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the Central region of human MOG.
NCBI Gene ID #:
4340
NCBI Official Name:
Myelin-oligodendrocyte glycoprotein
NCBI Official Symbol:
MOG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q16653
Protein GI Number:
317373391
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q16653
User NOte:
Optimal dilutions for each application to be determined by the researcher.