AFF2 Antibody

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ProSci
Product Code: PSI-59-677
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-677-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western blot analysis in 293 cell line lysates (35ug/lane).

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Further Information

Additional Names:
AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, FMR2P, Protein FMR-2, Protein Ox19, AFF2, FMR2, OX19
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
Background References:
  • Bensaid, M., et al. Nucleic Acids Res. 37(4):1269-1279(2009)
  • Brylawski, B.P., et al. Exp. Mol. Pathol. 82(2):190-196(2007)
  • Sharma, D., et al. Genet. Epidemiol. 20(1):129-144(2001)
  • Hillman, M.A., et al. J. Hum. Genet. 46(5):251-259(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AFF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 886-912 amino acids from the Central region of human AFF2.
NCBI Gene ID #:
2334
NCBI Official Name:
AF4/FMR2 family member 2
NCBI Official Symbol:
AFF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
145 kDa
Protein Accession #:
P51816
Protein GI Number:
116241242
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P51816
User NOte:
Optimal dilutions for each application to be determined by the researcher.