KLF1 Antibody
| Code | Size | Price |
|---|
| PSI-57-769-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF, KLF1, EKLF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a hematopoietic-specific transcription
factor that induces high-level expression of adult beta-globin and
other erythroid genes. The zinc-finger protein binds to the DNA
sequence CCACACCCT found in the beta hemoglobin promoter.
Heterozygous loss-of-function mutations in this gene result in the
dominant In(Lu) blood phenotype.
Background References:
- Borg, J., et al. Nat. Genet. 42(9):801-805(2010)
- Zhou, D., et al. Nat. Genet. 42(9):742-744(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Papachatzopoulou, A., et al. Hemoglobin 34(4):333-342(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human KLF1.
NCBI Gene ID #:
10661
NCBI Official Name:
Krueppel-like factor 1
NCBI Official Symbol:
KLF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q13351
Protein GI Number:
2501699
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q13351
User NOte:
Optimal dilutions for each application to be determined by the researcher.