ACCN3 Antibody
| Code | Size | Price |
|---|
| PSI-60-330-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1, ASIC3, ACCN3, SLNAC1, TNAC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the degenerin/epithelial
sodium channel (DEG/ENaC) superfamily. The members of this family
are amiloride-sensitive sodium channels that contain intracellular
N and C termini, two hydrophobic transmembrane regions, and a large
extracellular loop, which has many cysteine residues with conserved
spacing. The member encoded by this gene is an acid sensor and may
play an important role in the detection of lasting pH changes. In
addition, a heteromeric association between this member and ACCN1
has been observed as proton-gated channels sensitive to gadolinium.
Alternative splicing of this gene generates three transcript
variants encoding distinct isoforms.
Background References:
- Borzan, J., et al. Anesthesiology 113(3):647-654(2010)
- Wu, S., et al. Clin. Chim. Acta 411 (15-16), 1132-1136 (2010) :
- Ko, Y.L., et al. J. Hypertens. 26(11):2154-2160(2008)
- Su, X., et al. J. Biol. Chem. 281(48):36960-36968(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3.
NCBI Gene ID #:
9311
NCBI Official Name:
Acid-sensing ion channel 3
NCBI Official Symbol:
ASIC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q9UHC3
Protein GI Number:
82582992
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UHC3
User NOte:
Optimal dilutions for each application to be determined by the researcher.