NR2E3 Antibody
| Code | Size | Price |
|---|
| PSI-57-558-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Photoreceptor-specific nuclear receptor, Nuclear receptor subfamily 2 group E member 3, Retina-specific nuclear receptor, NR2E3, PNR, RNR
Application Note:
For WB starting dilution is: 1:1000
Background:
This protein is part of a large family of nuclear receptor
transcription factors involved in signaling pathways. Nuclear
receptors have been shown to regulate pathways involved in
embryonic development, as well as in maintenance of proper cell
function in adults. Members of this family are characterized by
discrete domains that function in DNA and ligand binding. This gene
encodes a retinal nuclear receptor that is a ligand-dependent
transcription factor. Defects in this gene are a cause of enhanced
S cone syndrome. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Clark, G.R., et al. Ophthalmology 117(11):2169-2177(2010)
- Yang, Y., et al. Invest. Ophthalmol. Vis. Sci. 51(4):2229-2235(2010)
- Khan, A.O., et al. Arch. Ophthalmol. 128(3):344-348(2010)
- Kanda, A., et al. Mol. Vis. 15, 2174-2184 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This NR2E3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human NR2E3.
NCBI Gene ID #:
10002
NCBI Official Name:
Photoreceptor-specific nuclear receptor
NCBI Official Symbol:
NR2E3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q9Y5X4
Protein GI Number:
8928275
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9Y5X4
User NOte:
Optimal dilutions for each application to be determined by the researcher.