KCNJ12 Antibody

ProSci
Product Code: PSI-59-354
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-354-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from human brain tissue lysate, using KCNJ12 Antibody at 1:1000 at each lane.

Western blot analysis of lysate from human brain tissue lysate, using KCNJ12 Antibody at 1:1000 at each lane.

Further Information

Additional Names:
ATP-sensitive inward rectifier potassium channel 12, Inward rectifier K(+) channel Kir22, IRK-2, Inward rectifier K(+) channel Kir22v, Potassium channel, inwardly rectifying subfamily J member 12, KCNJ12, IRK2, KCNJN1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Background References:
  • Collins, A., et al. J. Cell. Physiol. 219(1):8-13(2009)
  • Ji, W., et al. Nat. Genet. 40(5):592-599(2008)
  • Panama, B.K., et al. J. Physiol. (Lond.) 571 (PT 2), 287-302 (2006) :
  • Kiesecker, C., et al. J. Mol. Med. 84(1):46-56(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNJ12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human KCNJ12.
NCBI Gene ID #:
3768
NCBI Official Name:
ATP-sensitive inward rectifier potassium channel 12
NCBI Official Symbol:
KCNJ12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q14500
Protein GI Number:
77416868
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q14500
User NOte:
Optimal dilutions for each application to be determined by the researcher.