MEF2D Antibody
| Code | Size | Price |
|---|
| PSI-57-537-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Myocyte-specific enhancer factor 2D, MEF2D
Application Note:
For WB starting dilution is: 1:1000
Background:
MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
Background References:
- Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Aude-Garcia, C., et al. Biochem. J. 430(2):237-244(2010)
- Czubryt, M.P., et al. J. Biol. Chem. 285(22):16942-16950(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MEF2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human MEF2D.
NCBI Gene ID #:
4209
NCBI Official Name:
Myocyte-specific enhancer factor 2D
NCBI Official Symbol:
MEF2D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q14814
Protein GI Number:
2500876
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q14814
User NOte:
Optimal dilutions for each application to be determined by the researcher.