SPRR1A Antibody

ProSci
Product Code: PSI-64-004
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-64-004-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).

Western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).

Further Information

Additional Names:
Cornifin-A, 19 kDa pancornulin, SPRK, Small proline-rich protein IA, SPR-IA, SPRR1A
Application Note:
For WB starting dilution is: 1:1000
Background:
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Background References:
  • Jarzab, J., et al. Int. Arch. Allergy Immunol. 151(1):28-37(2010)
  • Stemmler, S., et al. Int. J. Immunogenet. 36(4):217-222(2009)
  • Kainu, K., et al. Exp. Dermatol. 18(2):109-115(2009)
  • Bonilla, I.E., et al. J. Neurosci. 22(4):1303-1315(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPRR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the C-terminal region of human SPRR1A.
NCBI Gene ID #:
6698
NCBI Official Name:
Cornifin-A
NCBI Official Symbol:
SPRR1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
P35321
Protein GI Number:
215273890
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P35321
User NOte:
Optimal dilutions for each application to be determined by the researcher.