BPNT1 Antibody
| Code | Size | Price |
|---|
| PSI-58-554-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP, BPNT1
Application Note:
For WB starting dilution is: 1:1000
Background:
BPNT1, also called bisphosphate 3-prime-nucleotidase, or
BPntase, is a member of a magnesium-dependent phosphomonoesterase
family. Lithium, a major drug used to treat manic depression, acts
as an uncompetitive inhibitor of BPntase. The predicted human
protein is 92% identical to mouse BPntase. BPntase's physiologic
role in nucleotide metabolism may be regulated by inositol
signaling pathways. The inhibition of human BPntase may account for
lithium-induced nephrotoxicity.
Background References:
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
- Spiegelberg, B.D., et al. J. Biol. Chem. 274(19):13619-13628(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BPNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1.
NCBI Gene ID #:
10380
NCBI Official Name:
3'(2'),5'-bisphosphate nucleotidase 1
NCBI Official Symbol:
BPNT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
O95861
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O95861
User NOte:
Optimal dilutions for each application to be determined by the researcher.