TULP3 Antibody
| Code | Size | Price |
|---|
| PSI-60-269-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tubby-related protein 3, Tubby-like protein 3, TULP3, TUBL3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the tubby gene family of
bipartite transcription factors. Members of this family have been
identified in plants, vertebrates, and invertebrates, and they
share a conserved N-terminal transcription activation region and a
conserved C-terminal DNA and phosphatidylinositol-phosphate binding
region. The encoded protein binds to phosphoinositides in the
plasma membrane via its C-terminal region and probably functions as
a membrane-bound transcription regulator that translocates to the
nucleus in response to phosphoinositide hydrolysis, for instance,
induced by G-protein-coupled-receptor signaling. It plays an
important role in neuronal development and function. Two transcript
variants encoding distinct isoforms have been identified for this
gene.
Background References:
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Ikeda, A., et al. J. Cell. Sci. 115 (PT 1), 9-14 (2002) :
- Santagata, S., et al. Science 292(5524):2041-2050(2001)
- Ikeda, S., et al. Invest. Ophthalmol. Vis. Sci. 40(11):2706-2712(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TULP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-400 amino acids from the C-terminal region of human TULP3.
NCBI Gene ID #:
7289
NCBI Official Name:
Tubby-related protein 3
NCBI Official Symbol:
TULP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
O75386
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O75386
User NOte:
Optimal dilutions for each application to be determined by the researcher.