RPH3A Antibody

ProSci
Product Code: PSI-57-500
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-500-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Rabphilin-3A, Exophilin-1, RPH3A, KIAA0985
Application Note:
For WB starting dilution is: 1:1000
Background:
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).
Background References:
  • Katkoori, V.R., et al. Front. Biosci. 13, 1050-1061 (2008) :
  • Smith, R., et al. J. Neurochem. 103(1):115-123(2007)
  • Lin, C.C., et al. J. Cell. Physiol. 211(2):316-326(2007)
  • Dalfo, E., et al. Neurobiol. Dis. 16(1):92-97(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This RPH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-686 amino acids from the C-terminal region of human RPH3A.
NCBI Gene ID #:
22895
NCBI Official Name:
Rabphilin-3A
NCBI Official Symbol:
RPH3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q9Y2J0
Protein GI Number:
13878745
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9Y2J0
User NOte:
Optimal dilutions for each application to be determined by the researcher.