TAC4 Antibody

ProSci
Product Code: PSI-56-689
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-689-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Further Information

Additional Names:
Tachykinin-4, Preprotachykinin-C, PPT-C, Endokinin-A, EKA, Endokinin-A/B, EKA/B, Endokinin-C, EKC, TAC4 (HGNC:16641)
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
  • Tran, A.H., et al. Neuropeptides 43(1):1-12(2009)
  • Cunningham, S., et al. J. Neuroimmunol. 183 (1-2), 208-213 (2007) :
  • Page, N.M. Vascul. Pharmacol. 45(4):200-208(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TAC4.
NCBI Gene ID #:
255061
NCBI Official Name:
Tachykinin-4
NCBI Official Symbol:
TAC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
12 kDa
Protein Accession #:
Q86UU9
Protein GI Number:
74723510
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q86UU9
User NOte:
Optimal dilutions for each application to be determined by the researcher.