KCNE4 Antibody
| Code | Size | Price |
|---|
| PSI-59-910-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Potassium voltage-gated channel subfamily E member 4, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, KCNE4
Application Note:
For WB starting dilution is: 1:1000
Background:
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. This gene encodes a member of
the potassium channel, voltage-gated, isk-related subfamily. This
member is a type I membrane protein, and a beta subunit that
assembles with a potassium channel alpha-subunit to modulate the
gating kinetics and enhance stability of the multimeric complex.
This gene is prominently expressed in the embryo and in adult
uterus.
Background References:
- Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
- Sole, L., et al. J. Cell. Sci. 122 (PT 20), 3738-3748 (2009) :
- Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)
- Manderfield, L.J., et al. J. Physiol. (Lond.) 587 (PT 2), 303-314 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This KCNE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human KCNE4.
NCBI Gene ID #:
23704
NCBI Official Name:
Potassium voltage-gated channel subfamily E member 4
NCBI Official Symbol:
KCNE4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q8WWG9
Protein GI Number:
311033433
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q8WWG9
User NOte:
Optimal dilutions for each application to be determined by the researcher.