SCN5A Antibody
| Code | Size | Price |
|---|
| PSI-60-210-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sodium channel protein type 5 subunit alpha, HH1, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav15, SCN5A
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an integral membrane
protein and tetrodotoxin-resistant voltage-gated sodium channel
subunit. This protein is found primarily in cardiac muscle and is
responsible for the initial upstroke of the action potential in an
electrocardiogram. Defects in this gene are a cause of long QT
syndrome type 3 (LQT3), an autosomal dominant cardiac disease.
Alternative splicing results in several transcript variants
encoding different isoforms.
Background References:
- Liu, M., et al. Circ. Res. 107(8):967-974(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- van Stuijvenberg, L., et al. DNA Cell Biol. 29(10):577-587(2010)
- House, C.D., et al. Cancer Res. 70(17):6957-6967(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This SCN5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human SCN5A.
NCBI Gene ID #:
6331
NCBI Official Name:
Sodium channel protein type 5 subunit alpha
NCBI Official Symbol:
SCN5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
227 kDa
Protein Accession #:
Q14524
Protein GI Number:
215273881
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q14524
User NOte:
Optimal dilutions for each application to be determined by the researcher.