GABRB2 Antibody
| Code | Size | Price |
|---|
| PSI-57-799-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, GABRB2
Application Note:
For WB starting dilution is: 1:500
Background:
The gamma-aminobutyric acid (GABA) A receptor is a
multisubunit chloride channel that mediates the fastest inhibitory
synaptic transmission in the central nervous system. This gene
encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome
5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2
subunits of the GABA A receptor. Alternative splicing of this gene
generates 2 transcript variants, differing by a 114 bp insertion.
Background References:
- Lo, W.Y., et al. J. Biol. Chem. 285(41):31348-31361(2010)
- Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Chen, J., et al. Biochem. Soc. Trans. 37 (PT 6), 1415-1418 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GABRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human GAB_2.
NCBI Gene ID #:
2561
NCBI Official Name:
Gamma-aminobutyric acid receptor subunit beta-2
NCBI Official Symbol:
GABRB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
P47870
Protein GI Number:
292495010
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P47870
User NOte:
Optimal dilutions for each application to be determined by the researcher.