KCND3 Antibody
| Code | Size | Price |
|---|
| PSI-57-570-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv43, KCND3
Application Note:
For WB starting dilution is: 1:1000
Background:
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shal-related subfamily, members of which form
voltage-activated A-type potassium ion channels and are prominent
in the repolarization phase of the action potential. This member
includes two isoforms with different sizes, which are encoded by
alternatively spliced transcript variants of this gene. [provided
by RefSeq].
Background References:
- Lundby, A., et al. Br. J. Pharmacol. 160(8):2028-2044(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Liang, P., et al. Biophys. J. 98(12):2867-2876(2010)
- Cotella, D., et al. Pflugers Arch. 460(1):87-97(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This KCND3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human KCND3.
NCBI Gene ID #:
3752
NCBI Official Name:
Potassium voltage-gated channel subfamily D member 3
NCBI Official Symbol:
KCND3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
Q9UK17
Protein GI Number:
92090984
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UK17
User NOte:
Optimal dilutions for each application to be determined by the researcher.