NHLH1 Antibody

ProSci
Product Code: PSI-58-789
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-789-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in WiDr cell line lysates (35ug/lane).

Western blot analysis in WiDr cell line lysates (35ug/lane).

Further Information

Additional Names:
Helix-loop-helix protein 1, HEN-1, Class A basic helix-loop-helix protein 35, bHLHa35, Nescient helix loop helix 1, NSCL-1, NHLH1, BHLHA35, HEN1
Application Note:
For WB starting dilution is: 1:1000
Background:
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM].
Background References:
  • Manetopoulos, C., et al. Biochem. Biophys. Res. Commun. 307(4):891-899(2003)
  • Bao, J., et al. Development 127(2):425-435(2000)
  • Lipkowitz, S., et al. J. Biol. Chem. 267(29):21065-21071(1992)
  • Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89(18):8492-8496(1992)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NHLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the Central region of human NHLH1.
NCBI Gene ID #:
4807
NCBI Official Name:
Helix-loop-helix protein 1
NCBI Official Symbol:
NHLH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
Q02575
Protein GI Number:
399885
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q02575
User NOte:
Optimal dilutions for each application to be determined by the researcher.