PTF1A Antibody
| Code | Size | Price |
|---|
| PSI-57-324-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF1P48
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is a component of the
pancreas transcription factor 1 complex (PTF1) and is known to have
a role in mammalian pancreatic development. The protein plays a
role in determining whether cells allocated to the pancreatic buds
continue towards pancreatic organogenesis or revert back to
duodenal fates. The protein is thought to be involved in the
maintenance of exocrine pancreas-specific gene expression including
elastase 1 and amylase. Mutations in this gene cause cerebellar
agenesis and loss of expression is seen in ductal type pancreas
cancers.
Background References:
- Meredith, D.M., et al. J. Neurosci. 29(36):11139-11148(2009)
- Rodolosse, A., et al. Biochem. J. 418(2):463-473(2009)
- Tutak, E., et al. Genet. Couns. 20(2):147-152(2009)
- Yamada, M., et al. J. Neurosci. 27(41):10924-10934(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the C-terminal region of human PTF1A.
NCBI Gene ID #:
256297
NCBI Official Name:
Pancreas transcription factor 1 subunit alpha
NCBI Official Symbol:
PTF1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q7RTS3
Protein GI Number:
74749931
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q7RTS3
User NOte:
Optimal dilutions for each application to be determined by the researcher.