KCNC4 Antibody

ProSci
Product Code: PSI-58-639
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-639-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv34, KCNC4
Application Note:
For WB starting dilution is: 1:1000
Background:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.
Background References:
  • Mosing, M.A., et al. Twin Res Hum Genet 13(4):398-403(2010)
  • Menendez, S.T., et al. J. Pathol. 221(4):402-410(2010)
  • Leblanc, N. Cardiovasc. Res. 86(3):351-352(2010)
  • Miguel-Velado, E., et al. Cardiovasc. Res. 86(3):383-391(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human KCNC4.
NCBI Gene ID #:
3749
NCBI Official Name:
Potassium voltage-gated channel subfamily C member 4
NCBI Official Symbol:
KCNC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
Q03721
Protein GI Number:
66774206
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q03721
User NOte:
Optimal dilutions for each application to be determined by the researcher.