SOX8 Antibody
Code | Size | Price |
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PSI-58-610-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Transcription factor SOX-8, SOX8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the SOX (SRY-related
HMG-box) family of transcription factors involved in the regulation
of embryonic development and in the determination of the cell fate.
The encoded protein may act as a transcriptional activator after
forming a protein complex with other proteins. This protein may be
involved in brain development and function. Haploinsufficiency for
this protein may contribute to the mental retardation found in
haemoglobin H-related mental retardation (ART-16 syndrome).
Background References:
- Nonaka, D. Am. J. Clin. Pathol. 131(5):731-736(2009)
- Hoff, S., et al. J. Comp. Neurol. 509(4):356-371(2008)
- Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
- Schepers, G., et al. J. Biol. Chem. 278(30):28101-28108(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.
NCBI Gene ID #:
30812
NCBI Official Name:
Transcription factor SOX-8
NCBI Official Symbol:
SOX8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P57073
Protein GI Number:
10720294
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P57073
User NOte:
Optimal dilutions for each application to be determined by the researcher.