NR4A3 Antibody
| Code | Size | Price |
|---|
| PSI-58-224-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear receptor subfamily 4 group A member 3, Mitogen-induced nuclear orphan receptor, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the steroid-thyroid
hormone-retinoid receptor superfamily. The encoded protein may act
as a transcriptional activator. The protein can efficiently bind
the NGFI-B Response Element (NBRE). Three different versions of
extraskeletal myxoid chondrosarcomas (EMCs) are the result of
reciprocal translocations between this gene and other genes. The
translocation breakpoints are associated with Nuclear Receptor
Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing
Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II,
TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome
17), or Transcription factor 12 (on chromosome 15). Multiple
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Novak, G., et al. Genes Brain Behav. 9(8):910-917(2010)
- Zhao, Y., et al. Circ. Res. 107(4):501-511(2010)
- Borup, R., et al. Endocr. Relat. Cancer 17(3):691-708(2010)
- Thompson, J., et al. Eur. J. Immunol. 40(7):2041-2049(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NR4A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-582 amino acids from the C-terminal region of human NR4A3.
NCBI Gene ID #:
8013
NCBI Official Name:
Nuclear receptor subfamily 4 group A member 3
NCBI Official Symbol:
NR4A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q92570
Protein GI Number:
90110039
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q92570
User NOte:
Optimal dilutions for each application to be determined by the researcher.