KCNAB3 Antibody
| Code | Size | Price |
|---|
| PSI-59-918-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Voltage-gated potassium channel subunit beta-3, K(+) channel subunit beta-3, Kv-beta-3, KCNAB3, KCNA3B
Application Note:
For WB starting dilution is: 1:1000
Background:
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shaker-related subfamily. This member is one of the
beta subunits, which are auxiliary proteins associating with
functional Kv-alpha subunits. This member and the KCNA5 gene
product assemble into a heteromultimeric A-type channel that
inactivates completely and is significantly faster than other
A-type Kv channels.
Background References:
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Leicher, T., et al. J. Biol. Chem. 273(52):35095-35101(1998)
- McCormack, K., et al. FEBS Lett. 370 (1-2), 32-36 (1995) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the Central region of human KCNAB3.
NCBI Gene ID #:
9196
NCBI Official Name:
Voltage-gated potassium channel subunit beta-3
NCBI Official Symbol:
KCNAB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
O43448
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O43448
User NOte:
Optimal dilutions for each application to be determined by the researcher.