ASCL1 Antibody
| Code | Size | Price |
|---|
| PSI-60-683-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46, ASCL1, ASH1, BHLHA46, HASH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the basic helix-loop-helix
(BHLH) family of transcription factors. The protein activates
transcription by binding to the E box (5'-CANNTG-3'). Dimerization
with other BHLH proteins is required for efficient DNA binding.
This protein plays a role in the neuronal commitment and
differentiation and in the generation of olfactory and autonomic
neurons. Mutations in this gene may contribute to the congenital
central hypoventilation syndrome (CCHS) phenotype in rare cases.
Background References:
- Phi, J.H., et al.Neurosurg Pediatr 5(6):608-614(2010)
- McGaughey, D.M., et al. Genomics 95(6):363-369(2010)
- Li, F., et al. Zhongguo Fei Ai Za Zhi 13(4):317-321(2010)
- Deng, H., et al. Biochem. Biophys. Res. Commun. 392(4):548-550(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ASCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1.
NCBI Gene ID #:
429
NCBI Official Name:
Achaete-scute homolog 1
NCBI Official Symbol:
ASCL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P50553
Protein GI Number:
20455478
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P50553
User NOte:
Optimal dilutions for each application to be determined by the researcher.