GABRE Antibody
Code | Size | Price |
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PSI-58-946-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilon, GABRE
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the ligand-gated ionic
channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid
(GABA) A receptor which is a multisubunit chloride channel that
mediates the fastest inhibitory synaptic transmission in the
central nervous system. This gene encodes an epsilon subunit. It is
mapped to chromosome Xq28 in a cluster comprised of genes encoding
alpha 3, beta 4 and theta subunits of the same receptor.
Alternatively spliced transcript variants have been identified, but
only one is thought to encode a protein.
Background References:
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Craddock, N., et al. Mol. Psychiatry 15(2):146-153(2010)
- Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
- Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GABRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GABRE.
NCBI Gene ID #:
2564
NCBI Official Name:
Gamma-aminobutyric acid receptor subunit epsilon
NCBI Official Symbol:
GABRE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
P78334
Protein GI Number:
13124728
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P78334
User NOte:
Optimal dilutions for each application to be determined by the researcher.