KCE1L Antibody

ProSci
Product Code: PSI-64-057
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-057-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of KCE1L Antibody in NCI-H460 cell line lysates (35ug/lane)

Western blot analysis of KCE1L Antibody in NCI-H460 cell line lysates (35ug/lane)

Further Information

Additional Names:
Potassium voltage-gated channel subfamily E member 1-like protein, AMME syndrome candidate gene 2 protein, KCNE1L, AMMECR2
Application Note:
For WB starting dilution is: 1:1000
Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome.
Background References:
  • Ravn, L.S., et al. Heart Rhythm 5(3):427-435(2008)
  • Lundquist, A.L., et al. Genomics 87(1):119-128(2006)
  • Ravn, L.S., et al. Am. J. Cardiol. 96(3):405-407(2005)
  • Yang, Y., et al. Am. J. Hum. Genet. 75(5):899-905(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCE1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human KCE1L.
NCBI Gene ID #:
23630
NCBI Official Name:
Potassium voltage-gated channel subfamily E member 1-like protein
NCBI Official Symbol:
KCNE1L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
Q9UJ90
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UJ90
User NOte:
Optimal dilutions for each application to be determined by the researcher.