Neuropilin-2 Antibody

ProSci
Product Code: PSI-55-925
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-925-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the Neuropilin-2 antibody detected the Neuropilin-2 protein (arrow).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the Neuropilin-2 antibody detected the Neuropilin-2 protein (arrow).

Further Information

Additional Names:
Neuropilin-2, Vascular endothelial cell growth factor 165 receptor 2, NRP2, VEGF165R2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Background References:
  • Rey-Gallardo, A., et al. Glycobiology 20(9):1139-1146(2010)
  • Geretti, E., et al. Mol. Cancer Res. 8(8):1063-1073(2010)
  • Guo-ping, W., et al. Ann Plast Surg 65(1):80-84(2010)
  • Nasarre, C., et al. Cell Adh Migr 3(4):383-389(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Neuropilin-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human Neuropilin-2.
NCBI Gene ID #:
8828
NCBI Official Name:
Neuropilin-2
NCBI Official Symbol:
NRP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105 kDa
Protein Accession #:
O60462
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O60462
User NOte:
Optimal dilutions for each application to be determined by the researcher.