UNC5D Antibody
| Code | Size | Price |
|---|
| PSI-56-833-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D, UNC5D, KIAA1777, UNC5H4
Application Note:
For WB starting dilution is: 1:1000
Background:
UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Wang, H., et al. Biochem. Biophys. Res. Commun. 370(4):594-598(2008)
- Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
- Zhong, Y., et al. Cereb. Cortex 14(10):1144-1152(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.
NCBI Gene ID #:
137970
NCBI Official Name:
Netrin receptor UNC5D
NCBI Official Symbol:
UNC5D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
106 kDa
Protein Accession #:
Q6UXZ4
Protein GI Number:
54036576
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q6UXZ4
User NOte:
Optimal dilutions for each application to be determined by the researcher.