NRXN3 Antibody
| Code | Size | Price |
|---|
| PSI-60-163-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Neurexin-3-beta, Neurexin III-beta, Neurexin-3-beta, soluble form, Neurexin-3-beta, C-terminal fragment, NRXN3-CTF, NRXN3, KIAA0743
Application Note:
For WB starting dilution is: 1:1000
Background:
Neurexins are a family of proteins that function in the
vertebrate nervous system as cell adhesion molecules and receptors.
They are encoded by several unlinked genes of which two, NRXN1 and
NRXN3, are among the largest known human genes. Three of the genes
(NRXN1-3) utilize two alternate promoters and include numerous
alternatively spliced exons to generate thousands of distinct mRNA
transcripts and protein isoforms. The majority of transcripts are
produced from the upstream promoter and encode alpha-neurexin
isoforms; a much smaller number of transcripts are produced from
the downstream promoter and encode beta-neurexin isoforms. The
alpha-neurexins contain epidermal growth factor-like (EGF-like)
sequences and laminin G domains, and have been shown to interact
with neurexophilins. The beta-neurexins lack EGF-like sequences and
contain fewer laminin G domains than alpha-neurexins. [provided by
RefSeq].
Background References:
- Saus, E., et al.Psychiatr Res 44(14):971-978(2010)
- Hotta, K., et al. J. Hum. Genet. (2010) In press :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen:
This NRXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 436-462 amino acids from the C-terminal region of human NRXN3.
NCBI Gene ID #:
9369
NCBI Official Name:
Neurexin-3-beta
NCBI Official Symbol:
NRXN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
Q9HDB5
Protein GI Number:
218512141
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9HDB5
User NOte:
Optimal dilutions for each application to be determined by the researcher.