COIL Antibody
| Code | Size | Price |
|---|
| PSI-57-958-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Coilin, p80-coilin, COIL, CLN80
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an integral component
of Cajal bodies (also called coiled bodies). Cajal bodies are
nuclear suborganelles of varying number and composition that are
involved in the post-transcriptional modification of small nuclear
and small nucleolar RNAs. The N-terminus of the coilin protein
directs its self-oligomerization while the C-terminus influences
the number of nuclear bodies assembled per cell. Differential
methylation and phosphorylation of coilin likely influences its
localization among nuclear bodies and the composition and assembly
of Cajal bodies. This gene has pseudogenes on chromosome 4 and
chromosome 14.
Background References:
- Shanbhag, R., et al. FEBS Lett. 584(20):4351-4356(2010)
- Tapia, O., et al. Chromosoma 119(5):527-540(2010)
- Toyota, C.G., et al. Chromosoma 119(2):205-215(2010)
- Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL.
NCBI Gene ID #:
8161
NCBI Official Name:
Coilin
NCBI Official Symbol:
COIL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
P38432
Protein GI Number:
585632
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P38432
User NOte:
Optimal dilutions for each application to be determined by the researcher.