TOR1A Antibody

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ProSci
Product Code: PSI-59-714
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-714-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Torsin-1A, Dystonia 1 protein, Torsin ATPase-1A, 364-, Torsin family 1 member A, TOR1A, DQ2, DYT1, TA, TORA
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq].
Background References:
  • Sharma, N., et al. Mov. Disord. 25(13):2183-2187(2010)
  • Kaiser, F.J., et al. Ann. Neurol. 68(4):554-559(2010)
  • Gavarini, S., et al. Ann. Neurol. 68(4):549-553(2010)
  • Granata, A., et al. Eur. J. Neurol. 17 SUPPL 1, 81-87 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TOR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human TOR1A.
NCBI Gene ID #:
1861
NCBI Official Name:
Torsin-1A
NCBI Official Symbol:
TOR1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
O14656
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O14656
User NOte:
Optimal dilutions for each application to be determined by the researcher.