DDX20 Antibody
Code | Size | Price |
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PSI-58-056-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein 20, DEAD box protein DP 103, Gemin-3, DDX20, DP103, GEMIN3
Application Note:
For WB starting dilution is: 1:1000
Background:
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
which has an ATPase activity and is a component of the survival of
motor neurons (SMN) complex. This protein interacts directly with
SMN, the spinal muscular atrophy gene product, and may play a
catalytic role in the function of the SMN complex on RNPs.
Background References:
- Todd, A.G., et al. J. Mol. Biol. 401(5):681-689(2010)
- Sun, X., et al. Cell Stress Chaperones 15(5):567-582(2010)
- Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
- Boni, V., et al. Pharmacogenomics J. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DDX20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-741 amino acids from the C-terminal region of human DDX20.
NCBI Gene ID #:
11218
NCBI Official Name:
Probable ATP-dependent RNA helicase DDX20
NCBI Official Symbol:
DDX20
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
Q9UHI6
Protein GI Number:
12643886
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UHI6
User NOte:
Optimal dilutions for each application to be determined by the researcher.