GRHL2 Antibody

ProSci
Product Code: PSI-56-882
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-882-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Further Information

Additional Names:
Grainyhead-like protein 2 homolog, Brother of mammalian grainyhead, Transcription factor CP2-like 3, GRHL2, BOM, TFCP2L3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).
Background References:
  • Werth, M., et al. Development 137(22):3835-3845(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Kang, X., et al. Oncogene 28(4):565-574(2009)
  • Tanaka, Y., et al. J. Hepatol. 49(5):746-757(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GRHL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the Central region of human GRHL2.
NCBI Gene ID #:
79977
NCBI Official Name:
Grainyhead-like protein 2 homolog
NCBI Official Symbol:
GRHL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
Q6ISB3
Protein GI Number:
74736618
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q6ISB3
User NOte:
Optimal dilutions for each application to be determined by the researcher.