SCNN1D Antibody

ProSci
Product Code: PSI-59-370
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-370-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Delta-ENaC, ENaCD, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D, DNACH
Application Note:
For WB starting dilution is: 1:1000
Background:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Background References:
  • Wesch, D., et al. Am. J. Physiol., Cell Physiol. 299 (4), C779-C790 (2010) :
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Bangel-Ruland, N., et al. Am. J. Respir. Cell Mol. Biol. 42(4):498-505(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SCNN1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human SCNN1D.
NCBI Gene ID #:
6339
NCBI Official Name:
Amiloride-sensitive sodium channel subunit delta
NCBI Official Symbol:
SCNN1D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
P51172
Protein GI Number:
116242784
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P51172
User NOte:
Optimal dilutions for each application to be determined by the researcher.