PER1 Antibody

ProSci
Product Code: PSI-58-728
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-728-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, PER1, KIAA0482, PER, RIGUI
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Background References:
  • Xia, H.C., et al. CanNeurol Sci 37(3):365-370(2010)
  • Soria, V., et al. Neuropsychopharmacology 35(6):1279-1289(2010)
  • Utge, S.J., et al. PLoS ONE(2), E9259 (2010) :
  • Zhu, Y., et al. Cancer Res. 69(24):9315-9322(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from the C-terminal region of human PER1.
NCBI Gene ID #:
5187
NCBI Official Name:
Period circadian protein homolog 1
NCBI Official Symbol:
PER1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
136 kDa
Protein Accession #:
O15534
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O15534
User NOte:
Optimal dilutions for each application to be determined by the researcher.