CHRNB4 Antibody

ProSci
Product Code: PSI-60-859
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-859-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
Neuronal acetylcholine receptor subunit beta-4, CHRNB4
Application Note:
For WB starting dilution is: 1:1000
Background:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Background References:
  • Zhang, H., et al. Neuropsychopharmacology 35(11):2211-2224(2010)
  • Saccone, N.L., et al. Genes Brain Behav. 9(7):741-750(2010)
  • Hansen, H.M., et al. Hum. Mol. Genet. 19(18):3652-3661(2010)
  • Amos, C.I., et al. J. Natl. Cancer Inst. 102(15):1199-1205(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CHRNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CHRNB4.
NCBI Gene ID #:
1143
NCBI Official Name:
Neuronal acetylcholine receptor subunit beta-4
NCBI Official Symbol:
CHRNB4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P30926
Protein GI Number:
2506129
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P30926
User NOte:
Optimal dilutions for each application to be determined by the researcher.